MOTS-c
MOTS-c is a mitochondrially encoded peptide studied in experimental metabolism research.
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Research areas
Evidence matrix
- Molecular identity
- Confirmed
MOTS-c is a mitochondrially encoded peptide with a defined sequence. A synthetic research product still needs its own identity and purity specification.
- Human research
- None
- Replication
- Single research group
- Clinical endpoints
- No clinical endpoints
- Safety
- Not adequately studied
- Approval
- No documented approval
The dimensions are presented separately and are not combined into an overall score.
What the source shows
The original study examined obesity and insulin resistance in mice, among other models.
- MOTS-c and metabolic homeostasis in experimental modelsAnimal study2015
U.S. National Library of Medicine (PubMed)
Accessed:
Research gaps
- ·Endogenous measurements and animal experiments do not establish effective or safe human injections.
- ·Short profile: not a complete benefit–risk assessment. Unlisted contraindications and interactions are not adequately established in this profile; missing information does not establish safety.
Mechanism
Models showed changes in metabolic pathways including AMPK.
- MOTS-c and metabolic homeostasis in experimental modelsAnimal study2015
U.S. National Library of Medicine (PubMed)
Accessed:
Study protocols
No sufficiently supported, exactly citable study protocols are available.
Calculator
Arithmetic based only on your entries. Not a dose or use recommendation.
Reported adverse effects
- ·Safety has not been adequately studied.
Contraindications and warnings
No reviewed information on this point has been recorded here yet. This does not mean there are no risks or contraindications.
Interactions
No reviewed information on this point has been recorded here yet. This does not mean there are no risks or contraindications.
Research gaps
- ·Endogenous measurements and animal experiments do not establish effective or safe human injections.
- ·Short profile: not a complete benefit–risk assessment. Unlisted contraindications and interactions are not adequately established in this profile; missing information does not establish safety.
- MOTS-c and metabolic homeostasis in experimental modelsAnimal study2015
U.S. National Library of Medicine (PubMed)
Accessed:
Sources
Sources checked: · Version 2
- MOTS-c and metabolic homeostasis in experimental modelsAnimal study2015
U.S. National Library of Medicine (PubMed)
Accessed: