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Growth HormoneHistorical approval

Sermorelin

GHRH(1–29)-NH₂

Sermorelin is a short GHRH analogue that stimulates growth hormone. It has a historical US approval as Geref; this does not validate anti-aging use of current compounded products.

Peptipedia explains research and prescribing information. It does not replace medical advice and is not an invitation to use a substance.

Research areas

GH secretion testingGrowth-hormone deficiency

Evidence matrix

Molecular identity
Confirmed

Sermorelin is GHRH(1–29)-NH₂; historical Geref medicines contained sermorelin acetate. Current compounded preparations are not automatically those products.

Human research
Moderate
Replication
Multiple independent groups
Clinical endpoints
Surrogate measures
Safety
Limited characterization
Approval
No documented approval

The dimensions are presented separately and are not combined into an overall score.

Approval context

Historical Geref approval; not a blanket approval of current sermorelin products.

Research gaps

  • ·No established anti-aging benefit in healthy adults
  • ·Historical approval data are product- and indication-specific