PT-141
Bremelanotide
PT-141 is bremelanotide. VYLEESI has US approval for acquired, generalized HSDD in premenopausal women.
Approvals
Peptipedia explains research and prescribing information. It does not replace medical advice and is not an invitation to use a substance.
Research areas
Evidence matrix
- Molecular identity
- Confirmed
PT-141 denotes bremelanotide, a defined melanocortin-receptor agonist peptide. The US approval applies to VYLEESI.
- Human research
- Strong
- Replication
- Single research group
- Clinical endpoints
- Symptom- or function-related
- Safety
- Characterized by prescribing information or extensive studies
- Approval
- US · Approved
The dimensions are presented separately and are not combined into an overall score.
What the source shows
Its indication is narrower than general libido enhancement.
- VYLEESI: US prescribing informationPrescribing information2024
U.S. National Library of Medicine (DailyMed)
Accessed:
Research gaps
- ·Approval data cannot be generalized to other populations.
- ·Short profile: not a complete benefit–risk assessment. Unlisted contraindications and interactions are not adequately established in this profile; missing information does not establish safety.
Mechanism
Bremelanotide activates melanocortin receptors.
- VYLEESI: US prescribing informationPrescribing information2024
U.S. National Library of Medicine (DailyMed)
Accessed:
Study protocols
No sufficiently supported, exactly citable study protocols are available.
Calculator
Arithmetic based only on your entries. Not a dose or use recommendation.
Reported adverse effects
- ·Nausea, transient blood-pressure elevation and hyperpigmentation are described.
Contraindications and warnings
- ·Contraindicated with uncontrolled hypertension or known cardiovascular disease.
Interactions
- ·May affect absorption of oral medicines.
Research gaps
- ·Approval data cannot be generalized to other populations.
- ·Short profile: not a complete benefit–risk assessment. Unlisted contraindications and interactions are not adequately established in this profile; missing information does not establish safety.
- VYLEESI: US prescribing informationPrescribing information2024
U.S. National Library of Medicine (DailyMed)
Accessed:
Sources
Sources checked: · Version 2
- VYLEESI: US prescribing informationPrescribing information2024
U.S. National Library of Medicine (DailyMed)
Accessed: